Nephrotic Syndrome: What It Is

The signs of nephrotic syndrome — heavy protein loss, swelling and high cholesterol — and how it is treated.

Last updated: 2026-09-24

Nephrotic syndrome is a condition where the kidneys leak a large amount of protein into the urine, causing swelling and other changes.

The main signs

  • Heavy protein in the urine (foamy urine)
  • Swelling, especially around the eyes and legs
  • Low blood protein and high cholesterol

Treatment

Treatment targets the underlying cause, often with medicines to reduce protein leak and control swelling and blood pressure.

Frequently asked questions

Is nephrotic syndrome kidney failure?

No — it is a pattern of kidney damage, but it can progress and needs proper treatment.

Sources

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