Lupus Nephritis: When Lupus Affects the Kidneys

How lupus can involve the kidneys, and how lupus nephritis is managed.

Last updated: 2026-09-24

Lupus nephritis is kidney inflammation caused by systemic lupus erythematosus (SLE), an autoimmune disease.

Signs

  • Protein or blood in the urine
  • Swelling
  • Rising blood pressure

Treatment

Treatment uses medicines to suppress the immune system and control blood pressure, guided by a kidney biopsy in many cases.

Frequently asked questions

Can lupus nephritis be treated?

Yes, with immunosuppressive medicines and careful monitoring — outcomes have improved a great deal.

Sources

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