Diabetes Medicines and the Kidneys
How diabetes medicines relate to kidney function, and why some doses change.
Last updated: 2026-09-24
Several diabetes medicines are processed by the kidneys, so doses often need adjusting as kidney function changes.
What to do
Never adjust diabetes medicine yourself. Your doctor reviews doses against your kidney function regularly.
Frequently asked questions
Is metformin safe with kidney disease?
It may need dose adjustment or a change in advanced kidney disease — your doctor decides.